Xiang-Dong Edward Guo
Dr. Guo ([email protected]) is a Professor of Biomedical Engineering and the Director of the Bone Bioengineering Laboratory.
Field of Specialization
Biomechanics: Bone Mechanics, Imaging Analysis of Bone Microstructure, Biomechanics of Bone Cells, Micropatterning of Cells, Mechanobiology of Bone
Academic Training
Colleges and Universities Attended
- 1980-1984
Undergraduate Study in Applied Mechanics
Department of Mechanics, Peking University, Beijing, P. R. China
B.S. in Applied Mechanics
Bachelor Thesis: Diffusion of Macromolecules Across the Arterial Wall in the Presence of Multiple Endothelial Injuries, Sponsor: Professor Gong-Bi Wen
Published: Guo, X. and Wen, G-B (1985) Diffusion of macromolecules Across the Arterial Wall in the Presence of Multiple Endothelial Injuries, Proceedings of the 1st National Youth Biomedical Engineering Conference of China (received Class Award), Anhui, P. R. China.
- 1984-1988
Doctoral Graduate Study in Biomechanics
Department of Mechanics, Peking University, Beijing, P. R. China
- 1988-1989
Doctoral Graduate Study in Mechanical Engineering
Department of Mechanical Engineering, The City College of the City University of New York, New York, New York
- 1989-1990
Graduate Study in Engineering Science
Division of Applied Sciences, Harvard University, Cambridge, Massachusetts
M.S. in Engineering Sciences
- 1990-1994
Doctoral Graduate Study in Medical Engineering and Medical Physics
Harvard-MIT Division of Health Science and Technology
Division of Applied Sciences, Harvard University, Cambridge, Massachusetts
Ph.D. in Medical Engineering and Medical Physics (Harvard University)
Ph.D. Thesis: Fatigue of Trabecular Bone, Sponsors: Professors Thomas A. McMahon, Wilson C. Hayes, and Lorna J. Gibson
Published: Michel, M. C., Guo, X.-D., Gibson, L. J., McMahon, T. A. and Hayes, W. C. (1993) Compressive Fatigue Behavior of Bovine Trabecular Bone, J. Biomechanics, 26, p453-463.
Guo, X. E., Gibson, L. J., McMahon, T. A., Keaveny, T. M. and Hayes, W. C. (1994) Finite Element Modeling of Damage Accumulation in Trabecular Bone Under Cyclic Loading, J. Biomechanics, 27, p145-155.
Keaveny, T. M., Guo, X. E., Watchtel, E. F., McMahon, T. A. and Hayes, W. C. (1994) Trabecular Bone Exhibits Fully Linear Elastic Behavior and Yields at Low Strains, J. Biomechanics, 27(9): 1127-1136.
Keaveny, T. M., Watchtel, E. F., Guo, X. E., and Hayes, W. C. (1994) The Mechanical Properties of Damaged Trabecular Bone, J. Biomechanics, 27(9): 1309-1318.Bowman, S. M., Guo, X. E., Cheng, D. W., Keaveny, T. M., Gibson, L. J., Hayes, W. C. and McMahon, T. A. (1998) Creep Contributes to the Fatigue Behavior of Bovine Trabecular Bone, J. Biomech. Eng., 120, p647-654.
Bowman, S. M., Guo, X. E., Cheng, D. W., Keaveny, T. M., Gibson, L. J., Hayes, W. C., and McMahon, T. A. (1998) Creep Contributes to the Fatigue Behavior of Bovine Trabecular Bone, J. Biomech. Eng., 120(5): 647-654.
Guo, X. E., and Gibson, L. J. (1999) Behavior of Intact and Damaged Honeycombs: A Finite Element Study, Intl. J. Mech. Eng., 41, p85-105.
- 1993-1996
Postdoctoral Research in Orthopaedic Bioengineering
Orthopaedic Research Laboratories, The University of Michigan, Ann Arbor, Michigan
Mentor: Professor Steven A. Goldstein
- 1997
Trainee of Summer Course in Physiology: Molecular Signal Transduction (funded by NIH training grant)
Marine Biology Laboratory, Woods Hole, Massachusetts
Employment Record and Professional Experience
1984-1988
Graduate Research Assistant, Department of Mechanics, Peking University, Beijing, P. R. China
1988-1989
Graduate Research Assistant, Department of Mechanical Engineering, The City College of the City University of New York
1990-1993
Graduate Research Assistant, Orthopaedic Biomechanics Laboratory, Harvard University Medical School
1993-1996
Postdoctoral Research Fellow, Orthopaedic Research Laboratories, University of Michigan
1996-1998
Assistant Professor of Mechanical Engineering, Department of Mechanical Engineering, Columbia University
1998-2001
Assistant Professor of Biomedical Engineering, Department of Biomedical Engineering, Columbia University
2001-2007
Associate Professor of Biomedical Engineering, (with tenure 2003) Department of Biomedical Engineering, Columbia University
2004-2007
Associate Professor of Dental and Craniofacial Bioengineering (in Dentistry), College of Dental Medicine, Columbia University
2007-present
Professor of Biomedical Engineering, Department of Biomedical Engineering, Columbia University
Research Appointments
1984-1988
Graduate Research Assistant, Department of Mechanics, Peking University
1988-1989
Graduate Research Assistant, Department of Mechanical Engineering, The City College of the City University of New York
1990-1993
Graduate Research Assistant, Orthopaedic Biomechanics Laboratory, Harvard University Medical School
1993-1996
Postdoctoral Research Fellow, Orthopaedic Research Laboratories, The University of Michigan
1996-2001
Associate in Orthopaedic Research, New York Orthopaedic Hospital Research Laboratory, New York-Presbyterian Hospital
1997-present
Director, Bone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University
2008
Adjunct Professor, School of Aeronautics and Astronautics, Xian Jiaotong University, Xian, P. R. China
Fellowships and Honors
1985
Class Award from the First National Youth Biomedical Engineering Conference of P. R. China.
1989
Graduate Fellowship, Division of Applied Sciences, Harvard University
1990
HST Graduate Fellowship, Harvard-MIT Division of Health Science and Technology
1992
The New Investigator Recognition Award, Orthopaedic Research Society
1994
Postdoctoral Trainee of National Institute on Aging
1995
National Research Service Award, National Institutes of Health
1997
Marine Biological Laboratory Summer Course Fellowship, Marine Biological Laboratory
1999
National Science Foundation CAREER Award
2006
Funds for Talented Professionals (Joint Research Fund for Overseas Chinese Young Scholars), National Natural Science Foundation of China
2006
Fellow, American Institute for Medical and Biological Engineering
Society and Membership
Member
American Society of Mechanical Engineers, since 1993
Member
American Society of Biomechanics, since 1993
Member
Orthopaedic Research Society, since 1995
Member
Sigma Xi Scientific Research Society since 1998
Member
American Association for the Advancement of Science, since 1998
Vice-Chair
Solid Mechanics Committee of Bioengineering Division of American Society of Mechanical Engineers, 2001
Track Chair
Orthopaedic Bioengineering Track, 2005 Annual Meeting of Biomedical Engineering Society
Member
US National Committee on Biomechanics since 2005
Member
Provisional Executive Committee, World Association of Chinese Biomedical Engineers
Track Chair
Cellular and Molecular Biomechanics, Orthopaedic Research Society 2005-2008
Member
World Council of Biomechanics, 2006-2018
Treasurer
World Association of Chinese Biomedical Engineers, 2007-2009
Member
Council, The Society for Physical Regulation in Biology and Medicine
President-Elect
International Chinese Hard Tissue Society 2009-2011
President
International Chinese Hard Tissue Society 2011-2013
Program Chair
The Society for Physical Regulation in Biology and Medicine, 2010-2011
Vice President
The Society for Physical Regulation in Biology and Medicine, 2011-2012
President
The Society for Physical Regulation in Biology and Medicine, 2012-2013
Member
Board of Directors, International Chinese Hard Tissue Society 2009-2011
Member
Program Committee of Orthopaedic Research Society, 2009-2010
Member
Membership Committee of Orthopaedic Research Society, 2010-2011
Vice Chair
Membership Committee of Orthopaedic Research Society, 2011-2012
Chair
Membership Committee of Orthopaedic Research Society, 2011-2012
Member
Board of Directors, Orthopaedic Research Society, 2012-2013
Review and Advisory Activities
Reviewer
Journal of Biomechanics, since 1994
Reviewer
ASME Journal of Biomechanical Engineering, since 1994
Reviewer
Journal of Orthopaedic Research, since 1996
Reviewer
Annals of Biomedical Engineering, since 1996
Reviewer
Bone, since 1996
Reviewer
Journal of Bone and Mineral Research, since 1997
Reviewer
International Journal of Structures and Solids, since 1997
Member
Board of Editors, Journal of Medical Biomechanics, since 2002
Editor-in-Chief
Molecular and Cellular Biomechanics, 2005-2007
Managing Editor
Frontier in Bioscience, since 2006
Editor-in-Chief
Cellular and Molecular Bioengineering, an official and international journal
Biomedical Engineering Society, since 2007
Associate Editor
Guest, Journal of Biomechanical Engineering, 2008-2009
Associate Editor
Journal of Biomechanical Engineering, 2009-
Associate Editor-in-Chief
Acta Mechanica Sinica, since 2008
Panelist
Biomedical Engineering and Research to Aid Persons with Disabilities, Research Grant Review Panel, March 1999
Ad Hoc Member
Special Emphasis Study Section, NIAMS of National Institutes of Health, October 2000
Panelist
Biomedical Engineering and Research to Aid Persons with Disabilities, CAREER Panel, January 2001
Member
Peer Review Panel of American Institute of Biological Sciences, USAMRMC Bone Health and Military Medical Readiness 2001, February, 2001
Panelist
NASA Center Grant Review, February 19-20, 2002
Ad Hoc Member
Orthopaedics Study Section, NIAMS of National Institutes of Health, March 2002
Site-Visitor
NASA Center Grant Site Visit Team, May 28-31, 2002
Panelist
Special Grant Review Committee, NIDCR of National Institutes of Health, June 19, 2003
Panelist
Special Panel for Program Project Grant, NIAMS of National Institutes of Health, October 2003
Panelist
Special Grant Review Committee, NIDCR of National Institutes of Health, June 17, 2004
Panelist
Special Emphasis Panel on MABS, National Institutes of Health, June 24, 2004
Ad Hoc Member
Skeletal Biology Structure and regeneration Study Section, NIAMS of National Institutes of Health, June 27-29, 2004
Panelist
Special Emphasis Panel, NIAMS of National Institutes of Health, December 14, 2004
Panelist
Special Emphasis Panel, NIAMS of National Institutes of Health, March 9, 2005
Panelist
Special Emphasis Panel, NIAMS of National Institutes of Health, April 8, 2005
Panelist
Special Emphasis Panel, NIAMS of National Institutes of Health, November 22, 2005
Standing Member
Skeletal Biology Structure and regeneration Study Section, NIAMS of National Institutes of Health since February 2005-2009.
Member
External Advisory Committee, Institute of Biomechanics and Medical Engineering, Tsinghua University, Beijing, China, since 2006