About the Bone Bioengineering Laboratory

The Bone Bioengineering Laboratory (BBL) in the Department of Biomedical Engineering at Columbia University and under the direction of Dr. X. Edward Guo was established in 1997. The goals of BBL are to:

  • Educate students in performing advanced research in bone biomechanics and bone bioengineering.
  • Apply basic engineering and biological principles to study microstructures and functions of bones.
  • Provide a collaborative research environment in biomedical engineering for undergraduate/graduate students.

The BBL has strong collaborative associations with the Orthopaedic Research Laboratory at the Columbia College of Physicians and Surgeons, the Regional Bone Center at Helen Hayes Hospital, the Cellular Engineering Laboratory, and the Biomaterials and Interface Tissue Engineering Laboratory, the Laboratory for Intelligent Imaging and Neural Computing, and the Biomedical Imaging Laboratory in the Department of Biomedical Engineering, the Musculoskeletal Biomechanics Laboratory in the Department of Mechanical Engineering, the Department of Pathology of St. George's Hospital at the University of London, UK.

The BBL is a multi-scale research lab, with technologies that enable the study of bone from the single cell to whole tissue level. We pursue projects in both basic science and clinical research. There are two main groups in the BBL:

To learn more about the lab, please browse the site for more in-depth research project descriptions

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group picture of lab in laser tag uniforms
picture of lab members
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