Publications

Click here to view a selection of the 20 most representative papers from the Bone Bioengineering Laboratory.

View papers from the BBL in PubMed.

Full Length Papers

1. Guo, X. and Wu, W-Y (1987) The Stokes Flow Produced by An Arbitrary Axisymmetric Oblate Body Moving Perpendicularly Toward An Infinite Flat Wall Along Its Minor Axis, Acta Scientiarum Naturalium Universitatis Pekinensis, 1:39-48.

2. Guo, X. and Wu, W-Y (1988) An Approach to the Mathematical Modeling of the Pulse Condition-the Displacement Wave, (Chinese) Journal of Biomechanics, 3(1):21-26.

3. Guo, X. and Wu, W-Y (1988) The Mathematical and Mechanical Models in Biomechanics of the Spine: Review, Foreign Medicine: Biomedical Engineering (P. R. China), 11(6):296-301.

4. Wu, W-Y, Liang, L. and Guo, X. (1990) The Mixed Finite Element Method for Axisymmetric Stokes Flow on the Unbounded Domains. Chinese Journal of Computational Physics, 7(3):294-302.

5. Guo, X. and Wu, W-Y (1991) Mechanical Analysis of Correction of Scoliosis by Means of Shape Memory Alloy Rods --- Simple Mathematical and Mechanical Model, Chinese Journal of Biomedical Engineering, 10(2):87-93.

6. Guo, X. D. and Cowin, S. C. (1992) Periosteal and Endosteal Control of Bone Remodeling Under Torsional Loading, J. Biomechanics, 25(6): 645-650.

7. Michel, M. C., Guo, X. D., Gibson, L. J., McMahon, T. A., and Hayes, W. C. (1993) Compressive Fatigue Behavior of Bovine Trabecular Bone, J. Biomechanics, 26(4-5): 453-463.

8. Guo, X. E., Gibson, L. J., McMahon, T. A., Keaveny, T. M. and Hayes, W. C. (1994) Finite Element Modeling of Damage Accumulation in Trabecular Bone Under Cyclic Loading, J. Biomechanics, 27(2): 145-155.

9. Keaveny, T. M., Guo, X. E., Watchtel, E. F., McMahon, T. A. and Hayes, W. C. (1994) Trabecular Bone Exhibits Fully Linear Elastic Behavior and Yields at Low Strains, J. Biomechanics, 27(9): 1127-1136.

10. Keaveny, T. M., Watchtel, E. F., Guo, X. E., and Hayes, W. C. (1994) The Mechanical Properties of Damaged Trabecular Bone, J. Biomechanics, 27(9): 1309-1318.

11. Gulberg, R. E., Caldwell, N. J., Guo, X. E., Goulet, R. W., Hollister, S. J., and Goldstein, S. A. (1997) Mechanical Stimulation of Tissue Repair in the Hydraulic Bone Chamber, J. Bone Miner. Res., 12(8): 1295-1302.

12. Guo, X. E. and Goldstein, S. A. (1997) Is trabecular Bone Tissue Different from Cortical Bone Tissue? Forma, 12:185-196.

13. Guo, X. E., Liang, L. C., and Goldstein, S. A. (1998) Micromechanics of osteonal cortical bone fracture, J. Biomech. Eng., 120(1):112-117.

14. Bowman, S. M., Guo, X. E., Cheng, D. W., Keaveny, T. M., Gibson, L. J., Hayes, W. C., and McMahon, T. A. (1998) Creep Contributes to the Fatigue Behavior of Bovine Trabecular Bone, J. Biomech. Eng., 120(5): 647-654.

15. Guo, X. E., and Gibson, L. J. (1999) Behavior of Intact and Damaged Honeycombs: A Finite Element Study, Intl. J. Mech. Sci., 41(1): 85-105.

16. Zysset, P.K., Guo, X.E., Hoffler, C.E., Moore, K.E., and Goldstein S.A. (1998) Mechanical properties of human trabecular bone lamellae quantified by nanoindentation, Technology and Health Care, 6(5): 429-432.

17. Sun, D. N., Gu, W. Y., Guo, X. E., Lai, W. M., and Mow, V. C. (1999) A Mixed Finite Element Formulation of Triphasic Mechano-electrochemical Theory for Charged, Hydrated Biological Soft Tissues, Int. J. Num. Methods Eng., 45(10): 1375-1402.

18. Zysset, P. K., Guo, X. E., Hoffler, C. E., Moore, K. E., and Goldstein, S. A. (1999) Elastic Modulus and Hardness of Cortical and Trabecular Bone Lamella Measured by Nanoidentation in the human femur, J. Biomech., 32(10):1005-1012.

19. Guo, X. E. and Goldstein, S. A. (2000) Vertebral Trabecular Bone Microscopic Tissue Elastic Modulus and Hardness Do Not Change in Ovarietomized Rats, J. Orthop. Res., 18(2): 333-336.

20. Schaffner, G., Guo, XD. E., Silva, M. J. and Gibson, L. J. (2000) Modeling Fatigue Damage Accumulation in Two-Dimensional Voronoi Honeycombs, Intl. J. Mech. Sci., 42(4): 645-656.

21. Guo, X. E., and Kim, C. H. (2002) Mechanical Consequence of Trabecular Bone Loss and Its Treatment: A Three-Dimensional Model Stimulation, Bone, 30(2): 404-411.

22. Guo, X. E., Eichler, M. J., Takai, E. and Kim, C. H. (2002) A Rat Tail Vertebrae Model for Trabecular Bone Adaptation Studies, J. Biomech. 35(3): 363-368.

23. Lai, W. M., Sun, D. D., Ateshian, G. A., Guo, X. E., and Mow, V. M. (2002) Electrical Signals for Chondrocytes in Cartilage, Biorheology, 39(1/2): 11-25.

24. Wang, C. C., Guo, X. E., Sun, D., Mow, V. C., Ateshian, G. A., and Hung, C. T. (2002) The Functional Environment of Chondrocytes within Cartilage Subjected to Compressive Loading: Theoretical and Experimental Approach, Biorheology, 39(1/2): 39-45.

25. Mow, V. C. and Guo, X. E. (2002) Mechano-Electrochemical Properties of Articular Cartilage: Their Inhomogeneities and Anisotropies, Annual Review in Biomedical Engineering, 4:175-209.

26. Kim, C. H., Takai, E., Zhou, H., von Stechow, D., Müller, R., Dempster, D. W., and Guo, X. E. (2003) Trabecular Bone Response to Mechanical and Parathyroid Hormone Stimulation: The Role of Mechanical Microenvironments, J. Bone and Miner. Res., 18(12): 2116-2125.

27. Hung, C. T., Lima, E G., Mauck, R. L., Takai, E., LeRoux, M. A., Lu, H. H., Stark, R. G., Guo, X. E., and Ateshian, G. A. (2003) Anatomically Shaped Osteochondral Constructs for Articular Cartilage Repair, J. Biomemch., 36(12):1853-1864.

28. Chua, S. C. Jr., Liu, S. M., Li, Q., Sun, A., DeNino, W. F., Heymsfield, S. B., and Guo, X. E. (2004) Transgenic Complementation of Leptin Receptor Deficiency. II. Increased Leptin Receptor Transgene Dose Effects on Obesity/diabetes and Fertility/lactation in Lepr-db/db mice, Am. J. Physiol. Endocrinol. Metab., 286(3):E384-392.

29. Sun, D. D., Guo, X. E., Likhitpanichkul, M., Lai, W. M., and Mow, V.C. (2004) The Influence of the Fixed Negative Charges on Mechanical and Electrical Behaviors of Articular Cartilage under Unconfined Compression, ASME J Biomech. Eng., 126(1):6-16.

30. Lu, X. L., Sun, D. D., Guo, X. E., Chen, F. H., Lai, W. M., and Mow, V. C. (2004) Indentation Determined Mechanoelectrochemical Properties and Fixed Charge Density of Articular Cartilage, Ann. Biomed. Eng. 32(3): 370-379.

31. Wan, L. Q., Miller, C., Guo, X. E., and Mow, V. C. (2004) Fixed Electrical Charges and Mobile Ions Affect the Measurable Mechano-Electrochemical Properties of Charged-Hydrated Biological Tissues: The Articular Cartilage Paradigm, Mechanics and Chemistry of Biosystems, 1(1):81-99.

32. Dong, X. N. and Guo, X. E. (2004) The dependence of transversely isotropic elasticity of human femoral cortical bone on porosity, J. Biomech., 37:1281-2187.

33. Takai, E., Mauck, R. L., Hung, C. T. and Guo, X. E. (2004) Osteocyte Viability and Regulation of Osteoblast Function in a 3D Trabecular Bone Explant under Dynamic Hydrostatic Pressure, Journal of Bone and Mineral Research, 19(9):1403-1410.

34. Dong, X. N. and Guo, X. E. (2004) Geometric Determinants to Cement Line Debonding and Osteonal Lamellae Failure in Osteon Pushout Tests, ASME J. Biomech. Eng., 126(3):387-390.

35. Dong, X. N., Zhang, X. H., Huang, Y. Y., and Guo, X. E. (2005) A Generalized Self-consistent Estimate for the Effective Elastic Moduli of Fiber-reinforced Composite Materials with Multiple Transversely Isotropic Inclusions, Int. J. Mech. Sc., 47(6): 922–940.

36. Takai, E., Costa, K. D., Shaheen, A., Hung, C. T., and Guo, X. E. (2005) Osteoblast Elastic Modulus Measured by Atomic Force Microscopy is Substrate Dependent, Annals of Biomedical Engineering, 33(7):963–971. (Cover Picture)

37. Dong, X. N., Zhang, X., and Guo, X. E. (2005) Interfacial Strength of Cement Lines in Human Cortical Bone, Mechanics and Chemistry of Biosystems, 2(2):63-68.

38. Lu, H. H., Jiang, J., Tang, A., Hung, C. T., and Guo, X. E. (2005) Development of Controlled Heterogeneityy on a Polymer-Ceramic Hydrogel Scaffold for Osteocondral Repair, Key Engineering Materials, 284-286:607-610.

39. Xu, X. L., Tang, T., Dai, K., Zhu, Z., Guo, X. E., Yu, C., Lou, J. (2005) Immune Response and Effect of Adenovirus-mediated Human BMP-2 Gene Transfer on the Repair of Segmental Tibial Bone Defects in Goats, Acta Orthopaedica, 76(5):637-646.

40. Hoffler, C. E., Guo, X. E., Zysset, P. K., and Goldstein, S. A. (2005) An Application of Nanoindentation Technique to Measure Bone Tissue Lamellae Properties, ASME J. Biomech. Eng., 127(7):1046-1053.

41. Likhitpanichkul, M., Guo, X. E., and Mow, V. C. (2005) The Effect of Matrix Tension-Comprression Nonlinearity and Fixed Charges on Chondrocyte Response in Cartilage, Molecular and Cellular Biomechanics, 2(4):191-204.

42. Takai, E., Landersberg, R., Katz, R. W., Hung, C. T., and Guo, X. E. (2006) Substrate modulation of Osteoblast Cell Adhesion Strength, Focal Adhesion Kinase Activation, and Responsiveness to Mechanical Stimuli, Molecular and Cellular Biomechanics, 3(1):1-12.

43. Dong, X. N., and Guo, X. E. (2006) Prediction of Cortical Bone Elastic Constants by A Two-Level Micromechanical Model Using A Generalized Self-Consistent Method, ASME Journal of Biomechanical Engineering, 128(3):309-316.

44. Ishii, Y., Thomas, A. O., Guo, X. E., Hung, C. T., and Chen, F. H. (2006) Localization and Distribution of Cartilage Oligomeric Matrix Protein in the Rat Intervertebral Disc, Spine, 31(14): 1539-1546.

45. Ho, M. M., Kelly, T. A., Guo, X. E., Ateshian, G. A., and Hung, C. T. (2006) Spatially Varying Material Properties of the Rat Caudal Intervertebral Disc, Spine, 31(15): E486-493.

46. Liu, X. S., Sajda, P., Saha, P. K., Wehrli, F. W., and Guo, X. E. (2006) Quantification of the Roles of Trabecular Microarchitecture and Trabecular Type in Determining the Elastic Modulus of Human Trabecular Bone, Journal of Bone and Mineral Research, 21(10):1608-1617.

47. Guo, X. E., Takai, E., Jiang, X., Xu, Q., Whitesides, G. M., Yardley, J. T., Hung, C. T., Chow, E. M., Hantschel, T., and Costa, K. D. (2006) Intracellular Calcium Waves in Bone Cell Networks Under Single Cell Nanoindentation, Molecular and Cellular Biomechanics, 3(3):95-107.

48. Freed, L. E., Guilak, F., Guo, X. E., Gray, M. L., Tranquillo, R., Holmes, J. W., Radisic, M., Sefton, M. V., Kaplan, D., and Vunjak-Novakovic, G. (2006) Advanced Tools for Tissue Engineering: Scaffolds, Bioreactors, and Signaling, Tissue Engineering, 12(12):3285-3305.

49. Lu, X. L., Miller, C., Chen, F. H., Guo, X. E., and Van C. Mow (2007) The Generalized Triphasic Correspondence Principle for Simultaneous Determination of the Mechanical Properties and Proteoglycan Content of Articular Cartilage by Indentation, Journal of Biomechanics, 40(11):2434-2441.

50. Kim, C. H., Zhang, X. H., Mikhail, G. von Stechow, D., Müller, R. Kim, H. S., and Guo, X. E. (2007) Effects of Thresholding Techniques on mnicro-CT Based Finite Element Models of Trabecular Bone, ASME Journal of Biomechanical Engineering, 129(4):481-486.

51. Sigmund, E. E., Cho, H., Chen, P., Byrnes, S., Song, Y. Q., Guo, X. E., and Brown, T. R. (2008) Diffusion-based MR Methods for Bone Structure and Evolution, Magnetic Resonance in Medicine, 59(1):28–39.

52. Liu, X. S., Sajda, P., Saha, P. K., Wehrli, F. W., Bevil, G., Keaveny, T. M., and Guo, X. E. (2008) Complete Volumetric Decomposition of Individual Trabecular Plates and Rods and Its Morphological Correlations with Anisotropic Elastic Moduli in Human Trabecular Bone, Journal of Bone Mineral Research, 23(2):223-235.

53. Huo B., Lu, X. L., Hung, C. T., Costa, K. D., Xu, Q., Whitesides, G. M., and Guo, X. E. (2008) Fluid Flow Induced Calcium Response in Bone Cell Network, Cellular and Molecular Bioengineering, 1(1):58-66. (Cover Picture)

54. Wan, L. Q., Jiang, J., Arnold, D. E., Guo, X. E., Lu, H. H., and Mow, V. C. (2008) Calcium Concentration Effects on the Mechanical and Biochemical Properties of Chondrocyte-Alginate Constructs, Cellular and Molecular Bioengineering, 1(1): 93-102.

55. Zhang, X. H., Liu, X. S., Vasilic, B., Wehrli, F. W., Benito, M., Rajapakse, C. S., Snyder, P. J., and Guo, X. E. (2008) In Vivo µMRI-Based Finite Element and Morphological Analyses of Tibial Trabecular Bone in Eugonadal and Hypogonadal Men before and after Testosterone Treatment, Journal of Bone Mineral Research, 23(9): 1426-1434.

56. Spalazzi, J. P., Dagher, E., Soty, S. B., Guo, X. E., Rodeo, S. A., and Lu, H. H. (2008) In Vivo Evaluation of A Multi-phased scaffold designed for Orthopaedic Interface Tissue Engineering and Soft Tissue-to-Bone Integration, Journal of Biomedical Materials Research A, 86(1): 1-12.

57. Liu, X. S., Zhang, X. H., Huang, A. H., Sajda, P., Ji, B., and Guo, X. E. (2008) Dynamic Simulation of Three Dimensional Architectural and Mechanical Alterations in Human Trabecular Bone during Menopause, Bone, 43(2):292-301.

58. Li, C. Q., Magland, J. F., Rajapakse, C. S., Guo, X. E., Zhang, X. H., Vasilic, B., and Wehrli, F. W. (2008) Implications of Resolution and Noise for In Vivo Micro-MRI of Trabecular Bone, Medical Physics, 35(12):5584-5594.

59. Shi, Y, Yadav, V. K., Suda, N., Liu, X. S., Guo, X. E., Myers, M. G. Jr., and Karsenty, G. (2008) Dissociation of the Neuronal Regulation of Bone Mass and Energy Metabolism by Leptin In Vivo, Proceedings of National Academies of Science, 105(51): 20529-20533.

60. Liu, X. S., Bevil, G., Keaveny, T. M., Sajda, P., and Guo, X. E. (2009) Micromechanical Analyses of Vertebral Trabecular Bone Based on Individual Trabeculae Segmentation of Plates and Rod, Journal of Biomechanics, 40(2): 249-256.

61. Lu, X. L., Mow, V. C., and Guo, X. E. (2009) Proteoglycans and Mechanical Behaviors of Condylar Cartilage, Journal of Dental Research, 88(3): 244-248.

62. Liu, X. S., Zhang, X. H., and Guo, X. E. (2009) Contributions of Trabecular Rods of Various Orientations in Determining the Elastic Properties of Human Vertebral Trabecular Bone, Bone, 45(2): 158-163 (Cover picture).

63. Yadav, V. K., Oury, F., Suda, N., Liu, Z., W. Gao, X. B., Confavreux, C., Klemenhagen, K. C., Tanaka, K. F., Gingrich, J. A., Guo, X. E., Tecott, L. H., Mann, J. J., Hen, H., Horvath, T. L., and Karsenty, G. (2009) A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure, Cell, 138: 976–989.

64. Rajapakse, C. S., Magland, J., Zhang, X. H., Liu, X. S., Wehrli, S. L., Guo, X. E., and Wehrli, F.W. (2009) Implications of Noise and Resolution on Mechanical Properties of Trabecular Bone Estimated by Image-based Finite-Element Analysis, Journal of Orthopaedic Research, 27(10): 1263-1271.
65. Butler, D.L., Goldstein, S. A., Guldberg, R. E., Guo, X. E., Kamm, R., Laurencin, C. T., McIntire, L. V., Mow, V. C., Nerem, R. M., Sah, R. L., Soslowsky, L. J., Spilker, R. L., and Tranquillo, R. T. (2009) The impact of biomechanics in tissue engineering and regenerative medicine, Tissue Engineering, B Review 15(4): 477-484.

66. Chan, M. E., Lu. X. L., Huo, B., Baik, A. D., Chiang, V., Guldberg, R. E., Lu, H. H., and Guo, X. E. (2009) A Trabecular Bone Explant Model of Osteocyte-Osteoblast Co-Culture for Bone Mechanobiology, Cellular and Molecular Bioengineering, 2(3): 405-415.

67. Cohen, A., Liu, X. S., Stein, E. M., McMahon, D. J., Rogers, H. F., LeMaster, J., Recker, R. R., Lappe, J. M., Guo, X. E., and Shane, E. (2009) Bone Microachitecture and Stiffness in Premenopausal Women with Idiopathic Osteoporosis, The Journal of Clinical Endocrinology & Metabolism, 94(11): 4351-4360.

68. Zaidi, M., Turner, C.H., Canalis, E., Pacifici, R., Sun, L., Iqbal, J., Guo, X. E., Silverman, S., Epstein, S., and Rosen, C.J. (2009) Bone loss or lost bone: rationale and recommendations for the diagnosis and treatment of early postmenopausal bone loss. Curr Osteoporos Rep. 7(4):118-126.

69. Huo, B. Lu, X. L., and Guo, X. E. (2010) Intracellular Calcium Wave Propagation in Linear and Looped Bone Cell Networks, Proceedings of the Royal Society A Mathematics, Physics, and Engineering Sciences, 368(1912): 617-633.

70. Yadav, V. K., Balaji, S., Suresh, P.S., Liu, X. S., Lu, X. L., Li, Z., Guo, X. E., Mann, J. J., Balapure, A. K., Medhamurthy, R., Vidal, M., Karsenty, G., Ducy, P. (2010) Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis, Nature Medicine, 16(3):308-312.

71. Shi, X., Liu, X. S., Wang, X., Guo, X. E., and Niebur, G. L. (2010) Effects of Trabecular Type and Orientation on Microdamage Susceptibility in Trabecular Bone, Bone, 46(5): 1260-1266. (Cover Picture)

72. Huo, B. Lu, X. L., Costa, K. D., Xu, Q. and Guo, X. E. (2010) An ATP-Dependent Mechanism Mediates Intercellular Calcium Signaling in Bone Cell Network under Single Cell Nanoindentation, Cell Calcium, 47(3): 234-241.

73. Cohen, A., Dempster, D. W., Müller, R., Guo, X. E., Nickolas, T. L., Liu, X. S., Zhang, X. H., Wirth, A. J., van Lenthe, G. H., Kohler, T., McMahon, D. J., Zhou, H., Rubin, M. R., Bilezikian, J. P., Lappe, J. M., Recker, R.R. and Shane E. (2010) Assessment of Trabecular and Cortical Architecture and Mechanical Competence of Bone by High-Resolution Peripheral Computed Tomography: Comparison with Transiliac Bone Biopsy, Osteoporosis Intl., 21(2): 263-273.

74. Lu, X. L., Wan, L. Q., Guo, X. E., and Mow, V. C. (2010) A Linearized Formulation of Triphasic Mixture Theory for Articular Cartilage, and Its Application to Indentation Analysis, J Biomechanics, 43(4):673-679.

75. Grayson, W. L., Fröhlich, M., Yeager, K., Bhumiratana, S., Chan, M. E., Cannizzaro, C., Wan, L. Q., Liu, X. S., Guo, X. E., and Vunjak-Novakovic, G. (2010) Engineering Anatomically-Shaped Human Bone Grafts: The Role of Medium Perfusion, Proceedings of National Academy of Science, 107(8): 3299-3304.

76. Shi Y., Oury, F., Yadav, V. K., Wess, J., Liu X. S., Guo, X. E., Murshed, M., and Karsenty, G. (2010) Signaling through the M(3) Muscarinic Receptor Favors Bone Mass Accrual by Decreasing Sympathetic Activity, Cell Metabolism, 11(3):231-238.

77. Wan, L. Q., Guo, X. E., and Mow, V. C. (2010) A Triphasic Orthotropic Laminate Model for Cartilage Curling Behavior: Fixed Charge Density versus Mechanical Properties Inhomogeneity, ASME J Biomech. Engr., 132(2):02450.

78. Liu, X. S., Zhang, X. H., Sekhon, K. K., Admas, M. F., McMahon, D. J., Bilezikian, J. P., Shane, E., and Guo, X. E. (2010) High-Resolution Peripheral Quantitative Tomography Can Assess Microstructural and Mechanical Properties of Human Distal Tibial Bone, Journal of Bone and Mineral Research, 25(4):746–756.

79. Liu, X. S., Cohen, A. Shane, E., Stein, E., Rogers, H., Kokolus, S. L., Yin, P. T., McMahon, D. J., Lappe, J. M., Recker, R. R., and Guo, X. E. (2010) Individual Trabeculae Segmentation (ITS)-Based Morphological Analyses of High-Resolution Peripheral Quantitative Computed Tomography Images Detects Abnormal Microarchitecture of Plate and Rod Microarchitecture in Premenopausal Women with Idiopathic Osteoporosis, Journal of Bone and Mineral Research, 25(7): 1496-1505.

80. Kulak, C. A., Borba, V. C., Jorgetti, V., Dos Reis, L. M., Liu, X. S., Kimmel, D. B., Kulak J. Jr., Rabelo, L. M., Zhou, H., Guo, X. E., Bilezikian, J. P., Boguszewski, C. L., Dempster, D. W. (2010) Skeletal Microstructure Abnormalities in Postmenopausal Women with Chronic Obstructive Pulmonary Disease, Journal of Bone and Mineral Research, 25(9): 1931-1940.

81. Liu, X. S., Zhang, X. H., Rajapakse, C. S., Wald, M. J., Magland, J., Sekhon, K. K., Adams, M. F., Sajda, P., Wehrli, F. W., and Guo, X. E. (2010) Accuracy of High-Resolution In Vivo Micro Magnetic Resonance Imaging for Measurements of Microstructural and Mechanical Properties of Human Distal Tibial Bone, Journal of Bone and Mineral Research, 25(9): 2039-2050.

82. Liu, X. S., Cohen, A., Shane, E., Yin, P. T., Stein, E. M., Rogers, H., Kokolus, S. L., McMahon, D. J., Lappe, J. M., Recker, R. R., Lang, T., and Guo, X. E. (2010) Bone Density, Geometry, Microstructure, and Stiffness: Relationships between Peripheral and Central Skeletal Sites Assessed by DXA, HR-pQCT, and cQCT in Premenopausal Women, Journal of Bone and Mineral Research, 25(10): 2229-2238.

83. Jiang, J., Tang, A., Ateshian, G. A., Guo, X. E., Hung, C. T., and Lu, H. H. (2010) Bioactive Stratified Polymer Ceramic-Hydrogel Scaffold for Integrative Osteochondral Repair, Annals of Biomedical Engineering, 38(6): 2183-2196.

84. Peng, S., Liu, X. S., Wang, T., Li, Z., Zhou, G., Luk, K. D., Guo, X. E., and Lu, W. W. (2010) In Vivo Anabolic Effect of Strontium on Trabecular Bone Was Associated with Increased Osteoblastogenesis of Bone Marrow Stromal Cells, J. Orthop. Res., 28(9): 1208-1214.

85. Rajapakse, C. S., Magland, J. F., Wald, M. J., Liu, X. S., Zhang, X. H., Guo, X. E., and Wehrli, F. W. (2010) Computational Biomechanics of the Distal Tibia from High-Resolution MR and Micro-CT Images, Bone, 47(3): 556-563.

86. Shi, X., Liu, X. S., Wang, X., Guo, X. E., and Niebur, G. L. (2010) Type and Orientation of Yielded Trabeculae during Overloading of Trabecular Bone along Orthogonal Directions, Journal of Biomechanics, 43(13): 2460-2466.

87. Wan, L. Q., Kang, S. M., Eng, G., Grayson, W. L., Lu, X. L., Huo, B., Gimble, J., Guo, X. E., Mow, V. C. and Vunjak-Novakovic, G. (2010) Geometric Control of Human Stem Cell Morphology and Differentiation, Integrative Biology, 2(7-8): 346-353.

88. Fang, G., Ji, B., Liu, X. S., and Guo, X. E. (2010) Quantification of Trabecular Bone Microdamage Using the Virtual Internal Bond Model and the Individual Trabeculae Segmentation Technique, Computational Methods in Biomechanics and Biomedical Engineering, 13(5): 605-615.

89. Baik, A. D., Lu, X. L., Qiu, J., Huo, B., Hillman, E. M.C., Dong, C., and Guo, X. E. (2010) Quasi-3D Cytoskeletal Dynamics of Osteocytes under Fluid Flow, Biophysical Journal, 99(9): 2812-2820.

90. Oury, F., Yadav, V. K., Wang, Y., Zhou, B., Liu, X. S., Guo, X. E., Tecott, L. H., Schutz, G., Means, A. R., and Karsenty, G. (2010) CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons, Genes and Development, 24(20): 2330-2342.

91. Stein, E. M., Liu, X. S., Nickolas, T. L., Cohen, A., Thomas, V., McMahon, D. J., Zhang, C., Yin, P. T., Cosman, F., Nieves, J., Guo, X. E., and Shane, E. (2010) Abnormal microarchitecture and reduced stiffness at the radius and tibia in postmenopausal women with fractures, Journal of Bone and Mineral Research, 5(12):2296-2305.

92. Fields, A. J., Lee, G. L., Liu, X. S., Jekir, M. G., Guo, X. E., and Keaveny, T. M. Influence of Vertical Trabeculae on the Compressive Strength of the Human Vertebra, Journal of Bone and Mineral Research, in press, 2011.

93. Peng, S., Liu, X. S., Zhou, G., Li, Z., Luk, K. D.-K., Guo, X. E., and Lu, W. W. Osteoprotegerin Deficiency Attenuates Strontium-Mediated Inhibition of Osteoclastogenesis and Bone Resorption, Journal of Bone and Mineral Research, in press, 2011.

94. Wan, L. Q., Jiang, J., Miller, E. D., Guo, X. E., Mow, V. C., and Lu, H. H. Matrix Deposition Modulates the Viscoelastic Shear Properties of Hydrogel-Based Cartilage Grafts, Tissue Engineering Series A, in press 2011.

95. Warren L Grayson, W. L., Marolt, D., Bhumiratana, S., Fröhlich, M., Guo, X. E., and Vunjak-Novakovic, G. Optimizing the Medium Perfusion Rate in Bone Tissue Engineering Bioreactors, Biotechnology and Bioengineering, in press, 2011.

96. Liu, X.S., Walker M.D., McMahon, D.J., Udesky, J., Liu, G., Bilezikian, J.P., and Guo, X. E. Skeletal Microstructure by High Resolution, Non-Invasive Imaging: Differences between Premenopausal Chinese-American and Caucasian Women, Journal of Bone and Mineral Research, in press, 2011.

97. Liu, X. S., McMahon D. J., Shane, E., and Guo, X. E. Individual Trabeculae Segmentation (ITS)-Based Morphological Analysis of Micro-Scale Images of Human Tibial Trabecular Bone at Limited Spatial Resolution, Journal of Bone and Mineral Research, in press, 2011.

98. Walker M. D., Liu, X. S., Stein, E. M., Zhou, B., Bezati, E., McMahon, D. J., Udesky, J., Liu, G., Shane, E., Guo, X. E., and Bilezikian, J. P. Bone Microarchitecture and Stiffness in Postmenopausal Chinese-American and White Women, Journal of Bone and Mineral Research, in press, 2011.

99. Kajimura, D., Hinoi, E., Ferron, M., Kode, A., Riley, K. J., Zhou, B., Guo, X. E. and Karsenty, G. Genetic Determination of the Cellular Basis of the Sympathetic Regulation of Bone Mass Accrual, Journal of Experimental Medicine, in press, 2011.

100. Stein, E. M., Liu, X. S., Nickolas, T. L., Cohen, A., Thomas, V., McMahon, D. J., Zhang, C., Zhou, B., Cosman, F., Nieves, J., Guo, X. E. , and Shane, E. (2011) Abnormal microarchitecture and stiffness in postmenopausal women with ankle fractures, The Journal of Clinical Endocrinology & Metabolism, 96(7):2041-2048.

101. Inose, H., Zhou, B., Yadav, V., Guo, X. E. , Karsenty, G. and Ducy, P. (2011) Efficacy of serotonin inhibition in mouse models of bone loss, Journal of Bone and Mineral Research, 26(9):2002-2011.

102. Hu, M., Li, P., Lü, D., Sun, S., Lomg, M., Guo, X. E. , and Huo, B. (2011) Calcium response in osteoblastic pattern without gap junction under flow shear stress, Journal of Medical Biomechanics, 26(5):402-407.

103. Peng S., Liu, X. S., Huang, S., Li, Z., Pan, H., Zhen, W., Luk, K. D., Guo, X. E. , Lu, W. W. (2011) The Cross-talk between Osteoclasts and Osteoblasts in Response to Strontium Treatment: Involvement of Osteoprotegerin, Bone, 49(6):1290-1298.

104. Correia, C., Grayson, W. L., Park, M., Hutton, D., Zhou, B., Guo, X. E. , Niklason, L., Sousa, R. A., Reis, R. L., Vunjak-Novakovic, G. (2011) In Vitro Model of Vascularized Bone: Synergizing Vascular Development and Osteogenesis, PLoS ONE, 6(12): E28352.

105. Liu, X. S., Stein, E. M., Nickolas, T. L., Cohen, A., Thomas, V., McMahon, D. J., Zhang, C., Zhou, B., Cosman, F., Nieves, J., Shane, E. and Guo, X. E. (2012) Individual Trabeculae Segmentation (ITS)-Based Morphological Analyses of High-Resolution Peripheral Quantitative Computed Tomography Images Discriminate Fracture Status in Post-menopausal Women Independent of BMD, Journal of Bone and Mineral Research, 27(2): 263-272.

106. Lu, X. L., Huo B., Chiang, V. C., Baik, A. D., andGuo, X. E. (2012) Osteocytic Network Is More Responsive in Calcium Signaling than Osteoblastic Network under Fluid Flow, Journal of Bone and Mineral Research, 27(3): 563-574.

107. Qiu, J., Baik, A. D., Lu, X. L., Zhuang, Z., Hillman, E. M.-C., and Guo, X. E. (2012) Theoretical Basis of Quasi-3D Intracellular Strain Measurements, Cellular and Molecular Bioengineering, 5(2):165-172.

108. Wei, J., Shi, Y., Zheng, L., Zhou, B., Inose, H., Wang, J.,Guo, X. E. , Grosschedl, R., and Karsenty, G. (2012) miR-34s Inhibit Proliferation and Osteoblast Differentiation in the Mouse by Targeting SATB2, Journal of Cellular Biology, 197(4):509-521.

109. Lu, X. L., Huo, B. Park, M., andGuo, X. E. (2012) Calcium Responses in Osteocyteic Network under Steady and Oscillatory Flow, Bone, 51(3):466-473.

110. Kode, A., Mosialou, I., Silva, B. C., Rached, M., Zhou, B., Wang, J., Townes, T. M., Hen, R., DePinho, R. A., Guo, X. E. , and Kousteni, S. (2012) FoxO1 Orchestrates the Bone Suppressing Function of Gut Serotonin, Journal of Clinical Investigation, 122(10):3490-3503.

111. Wang, H., Ji, B., Liu, X. S., Guo, X. E. , Huang, Y., and Hwang, K.-C. (2012) Analysis of microstructural and mechanical alterations of trabecular bone in a simulated three-dimensional remodeling process, Journal of Biomechanics, 45(14):2417-2425.

112. Stein, E. M., Liu, X. S., Nickolas, T. L., Cohen, A., McMahon, D. J., Zhou, B., Zhang, C., Kamanda-Kosseh, M., Cosman, F., Nieves, J., Guo, X. E. , and Shane, E. (2012) Microarchitectural Abnormalities Are More Severe in Postmenopausal Women with Vertebral Compared to Nonvertebral Fractures, Journal of Clinical Endocrinology and Metabolism, 97(10):E1918-1926.

113. Cohen, A., Lang, T. F., McMahon, D. J., Liu, X. S., Guo, X. E. , Zhang, C., Stein, E. M., Dempster, D. W., Young, P., Recker, R. R., and Shane, E. (2012) Central QCT Reveals Cortical and Trabecular Structural Defects in Premenopausal Women with Idiopathic Osteoporosis, Regardless of Fracture History, Journal of Clinical Endocrinology and Metabolism, 97(11):4244-4252.

114. Brown, G., Butler, P. J., Chang, D. W., Chien, S., Clegg, R. M., Dewey, C. F., Dong, C., Guo, X. E., Helmke, B. P., Hess, H., Jacobs, C. R., Kaunas, R. R., Kumar, S., Lu, H. H., Mathur, A. B., Mow, V. C., Schmid-Schönbein, G. W., Skoracki, R., Wang, N., Wang, Y., Zhu, C. (2012) Cell Mol Bioeng., 5(3):239-253.

115. Jing, D., Lu, X. L., Leong, P. L., Sajda, P., and Guo, X. E. (2013) Spatiotemporal Properties of Intracellular Calcium [Ca2+]i Signaling in Osteocytic and Osteoblastic Cell Networks under Fluid Flow, Bone, 53(2):531-540.

116. Stein, E. M., Cohen, A., Young, P., Bucovsky, M., Zhang, C., Schrope, B. A., Bessler, M., Zhou, B., Wang, J., Guo, X. E. , and Shonni, S. J. (2013) Bariatric Surgery Results in Cortical Bone Loss, Journal of Clinical Endocrinology and Metabolism, 98(2):541-549.

117. Baik, A. D., Qiu, J., Hillman, E. M.-C., Dong, C., andGuo, X. E. (2013) Simultaneous Tracking of 3D Actin and Microtubule Strains in Individual MLO-Y4 Osteocytes under Oscillatory Flow, Biochem Biophys Res Commun., 431(4):718-723.

118. Stein, E. M, Silva, B. C., Boutroy, S., Zhou, B., Wang, J., Udesky, J., Zhang, A. C., McMahon, D. J., Romano, M., Dworakowski, E., Costa, A., Cusano, N., Irani, D., Cremers, S., Shane, E., Guo, X. E. , and Bilezikian, J. P. (2013) Primary Hyperparathyroidism is Associated with Abnormal Cortical and Trabecular Microstructure and Reduced Bone Stiffness in Postmenopausal Women, Journal of Bone and Mineral Research, 28(5):1029-1040.

119. Walker M. D., Liu, X. S., Zhou, B., Agarwal, S., Liu, G., McMahon, D. J., Bilezikian, J. P., and Guo, X. E. (2013) Pre- and Postmenopausal Differences in Bone Microstructure and Mechanical Competence in Chinese-American and White Women, Journal of Bone and Mineral Research, 28(6):1308-1318.

120. Liu, X. S., Wang, J., Zhou, B., Stein, E. M., Shi, X., Adams, M., Shane, E., and Guo, X. E. (2013) Fast Trabecular Bone Strength Predictions of HR-pQCT and Individual Trabeculae Segmentation (ITS)-Based Plate and Rod Finite Element Model Discriminate Postmenopausal Vertebral Fractures, Journal of Bone and Mineral Research, 28(7):1666-1678.

121. Cohen, A., Dempster, D. W., Recker, R. R., Lappe, J. L., Zhou, H., Zwahlen, A., Müller, R., Zhao, B.,Guo, X. E. , Lang, T., Saeed, I., Liu, X. S., Guo, X. E., Cremers, S., Rosen, C. J., Stein, E. M., Nicholas, T. L., McMahon, D. J., Young, P., and Shane, E. (2013) Abdominal fat is associated with lower bone formation and lower trabecular bone volume in healthy premenopausal women: a transiliac bone biopsy study, Journal of Clinical Endocrinology and Metabolism, 98(6):2562-2572.

122. Wang, H., Liu, X S., Zhou, B., Wang, J., Ji, B., Huang, Y., K.-C., Hwang, and Guo, X. E. (2013) Accuracy of Individual Trabeculae Segmentation Based Plate-Rod Finite Element Models of Idealized Trabecular Bone Microstructure, Journal of Biomechanical Engineering, 135(044502):1-5.

123. Ural, A., Bruno, P., Zhou, B., Shi, X. T., Shane, E., and Guo, X. E. (2013) Fracture Risk Evaluation of Human Radius Using A Coupled HR-pQCT Imaging and Fracture Mechanics-Based Finite Element Modeling Approach, Journal of Biomechanics, 46(7):1305-1311.
124. Silva, B., C., Zhang, C., Boutroy, S., McMahon, D., J., Zhou, B., Wang, J., Udesky, J., Cremers, S., Sarquis, M., Guo, X. E., Hans, D., and Bilezikian, J. P. (2013) Trabecular Bone Score – TBS – a novel method to evaluate bone microarchitecture in patients with Primary Hyperparathyroidism, Journal of Clinical Endocrinology and Metabolism, 98(5):1963-1970.

125. Fu, R., Liu, Q., Song, G., Baik, A., Hu, M., Sun, S., Guo, X. E. , Long, M., and Huo, B. (2013) Spreading Area and Shape Regulate Apoptosis and Differentiation of Osteoblasts, Biomedical Materials, 8(5):055005.

126. Wang, J., Zhou, B., Parkinson, I., Thomas, C. D., Clement, J. G., Fazzalari, N., and Guo, X. E. (2013) Trabecular Plate Loss and Deteriorating Elastic Modulus of Femoral Trabecular Bone in Intertrochanteric Hip Fractures, Bone Research, 1(4): 346-354.

127. Qiu, J., Baik, A. D., Lu, X. L., Hillman, E. M. C., Zhuang, Z., Dong, C. and Guo, X. E. (2014) A Noninvasive Approach to Determine Viscoelastic Properties of an Individual Adherent Cell under Fluid Flow, Journal of Biomechanics, 47(6):1537-1541.

128. Peng, S., Liu, X. S., Wang, F., Li, Z., Pan, H., Zhen, W., Luk, K. D. K.,Guo, X. E. , Lu, W. W. (2014) Intervention Timing of Strontium Treatment on Estrogen Depletion-Induced Osteoporosis in Rats: Bone Microstructure and Mechanics, Journal of Orthopaedic Research, 32(3):477-484.

129. Kajimura, D., Lee, H. W., Riley, K. J., Arteaga-Solis, E., Ferron, M., Zhou, B., Clarke, C. J., Hannun, Y. A., DePinho, R. A., Guo, X. E. , Mann, J. J., Karsenty, G. (2013) Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1, Cell Metabolism, 17(6):901-915.

130. Yin, M. T., Broun, E., Shah, J., Zhang, C. A., Foca, M., Neu, N., Nelson, J. A., Nishiyama, K. K., Zhou, B., Guo, X. E. , Bell, D. L., Shane, E., Arpadi, S. (2014) Lower peak bone mass and abnormal trabecular and cortical microarchitecture in young men infected with HIV early in life, AIDS, 28(3):345-353.

131. Boutroy, S., Walker, M. D., Liu, X. S., McMahon, D. J., Liu, G., Guo, X. E. , and Bilezikian, J. P. (2014) Lower Cortical Porosity and Higher Tissue Mineral Density in Chinese-American versus White Women, Journal of Bone and Mineral Research, 29(3):551-561.

132. Wang, H., Ji, B., Liu, X. S., van Oers, R. F., Guo, X. E. , Huang Y., Hwang K.C. (2014) Three-Dimensional Osteocyte-Viability-Based Bone Remodeling (OVBR) Model for Studying Bone Loss and Recovery under Disuse and Reloading Conditions, Biomechanics and Modeling in Mechanobiology, 13(1):153-166.

133. Jing, D., Baik, A. D., Lu, X. L., Zhou, B., Lai, X., Wang, L. Luo, E., and Guo, X. E. (2014) In Situ Intracellular Calcium Oscillations in Osteocytes in Intact Mouse Long Bones under Dynamic Mechanical Loading, FASEB Journal, 28(4):1582-1592.

134. Stein, E. M., Kepley, A., Walker, M., Zhou, B., Nickolas, T. L., Nishiyama, K., Liu, X. S., McMahon, D. J., Zhang, C., Boutroy, S., Cosman, F., Nieves, J., Guo, X. E. , and Shane, E. (2014) Skeletal Structure in Postmenopausal Women with Osteopenia and Fractures is Characterized by Abnormal Trabecular Plates and Cortical Thinning, Journal of Bone and Mineral Research, 29(5):1101-1109.

135. Iyer, S. P., Nikkel, L. E., Nishiyama, K., K., Zhang, C., McMahon, D., J., Boutroy, S., Liu, X. S., Ratner, L., Cohen, D. J., Guo, X. E. , Shane, E., and Nicholas, T. L. (2014) Kidney transplantation with early corticosteroid withdrawal immunosuppression: paradoxical effects at the central and peripheral skeleton, Journal of American Society of Nephrology, 25(6):1331-1341.

136. Zhou, B., Liu, X. S., Wang, J., Fields, A., Lu, X. L., and Guo, X. E. (2014) Dependence of Mechanical Properties of Trabecular Bone on Plate-Rod Microstructure Determined by Individual Trabecula Segmentation (ITS), Journal of Biomechanics, 47(3):702-708.
137. Nishiyama, K. K., Cohen, A., Young, P., Wang, J., Lappe, J. M., Guo, X. E., Recker, R. R., and Shane, E. (2014) Improved bone microarchitecture and strength in teriparatide-treated premenopausal women with idiopathic osteoporosis: An HR-pQCT study, Journal of Clinical Endocrinology and Metabolism, 99(7):2418-2425.

138. Bramlett, H. M., Dietrich, W. D., Marcillo, A., Mawhinney, L. J., Furones-Alonso, O., Bregy, A., Peng, Y., Wu, Y., Pan, J., Wang, Ji, Guo, X. E. , Bauman, W. A., Cardozo, C., Qin, W. (2014) Effects of Low Intensity Vibration on Bone and Muscle in Rats with Spinal Cord Injury, Osteoporosis International, 25(9):2209-2219.

139. Walker, M. D., Shi, S., Russo, J. J., Liu, X. S., Zhou, B., Zhang, C., Liu, G., McMahon, D. J., Bilezikian, J. P., and Guo, X. E. (2014) A Trabecular Plate-like Phenotype is Overrepresented in Chinese-American versus Caucasian Women, Osteoporosis International, 25(12):2787-2795.

140. Sutter, S., Nishiyama, K. K., Kepley, A., Zhou, B., Wang, J., McMahon, D. J.,Guo, X. E. and Stein, E. M. (2014) Abnormalities in Cortical Bone, Trabecular Plates, and Stiffness in Postmenopausal Women Treated with Glucocorticoids, Journal of Clinical Endocrinology and Metabolism, 99(11):4231-4240.

141. Zhou, B., Wang, J., Stein, E. M., Zhang, Z., Nishiyama, K. K., Zhang, C. A., Nikolas, T. L., Shane, E., and Guo, X. E. , (2014) Bone Density, Microarchitecture, and Stiffness in Caucasian and Caribbean Hispanic Postmenopausal American Women, Bone Research, 2:14016.

142. Wang, J., Zhou, B., Liu, X. S., Fields, A. J., Sanyal, A., Shi, X., Adams, M., Keaveny, T. M., and Guo, X. E. (2015) Trabecular Plates and Rods Determine Elastic Modulus and Yield Strength of Human Trabecular Bone, Bone, 72(3):71–80.

143. Stein EM, Rogers H, Leib A, McMahon DJ, Young P, Nishiyama K, Guo, XE , Lewis S, Green PH, Shane E. (2015) Abnormal Skeletal Strength and Microarchitecture in Women With Celiac Disease, Journal of Clinical Endocrinology and Metabolism, 100(6):2347-2353.

144. Jepsen, K. J., Silva, M. J., Vashishth, D., Guo, X. E. , and van der Meulen, M. (2015) Establishing Biomechanical Mechanisms in Mouse Models: Practical Guidelines for Systematically Evaluating Phenotypic Changes in Long Bones, Journal of Bone and Mineral Research, 30(6):951-966.

145. Wang, J., Kazakia, G. J., Zhou, B., Shi, X. T., and Guo, X. E. (2015) Distinct Tissue Mineral Density in Plate and Rod-like Trabeculae of Human Trabecular Bone, Journal of Bone and Mineral Research, 30(9):1641-1650.

146. Zhou, B., Zhang, Z., Wang, J., Yu, Y. E., Liu, X. S., Nishiyama, K. K., Rubin, M. R., Shane, E., Bilezikina, J. P., and Guo, X. E. . In Vivo Precision of Digital Topological Skeletonization Based Individual Trabecula Segmentation (ITS) Analysis of Trabecular Microstructure at the Distal Radius and Tibia by HR-pQCT, Pattern Recognition Letter, in press, 2015.

147. Jing Fu, J., Li, S., Feng, R., Ma, H., Sabeh, F., Roodman, G. D., Wang, J., Robinson, S., Guo, X. E. , Mapara, M. Y., Weiss, S. J., and Lentzsch, S. Multiple Myeloma-derived MMP-13 Mediates Osteoclast Fusogenesis and Osteolytic Disease, Journal of Clinical Investigations, in press, 2015.

148. Chen, Y., Wang, T., Guan, M., Zhao, W., Leung, F. K., Pan, H., Cao, X., Guo, X. E. , and Lu, W. W. Bone Turnover and Articular Cartilage Differences Localized to Subchondral Cysts in Knees with Advanced Osteoarthritis, Osteoarthritis and Cartilage, in press, 2015.

149. Cusano, N. E., Nishiyama, K. K., Zhang, C., Rubin, M. R., Boutroy, S., McMahon, D. J., Guo, X. E. , and Bilezikian, J. P. Noninvasive Assessment of Skeletal Microstructure and Estimated Bone Strength in Hypoparathyroidism, Journal of Bone and Mineral Research, in press, 2015.

150. Brown, G. Sattler, R. and Guo, X. E. Experimental Studies of Bone Mechanoadaptation: Bridging In Vitro and In Vivo Studies with Multiscale Systems, Journal of The Royal Society Interface, in press, 2015.

Book Chapters

1. Guo, X. E. (2000) Mechanical Properties of Cortical Bone and Cancellous Bone Tissue, in Bone Mechanics Handbook, 2nd Edition, Edited by S. C. Cowin, CRC Press, Boca Raton, Florida, pp. (10-1)-(10-23).

2. Mow, V. C., Sun, D. N., Guo, X. E., Likhitpanichkul, M., and Lai, W. M. (2002) Fixed Negative Charges Modulate Mechanical Behaviors and Electrical Signals in Articular Cartilage: A Triphasic Paradigm, in Porous Media: Theoretical, Experimental and Numerical Applications, Edited by W. Ehlers and J. Bluhm, Springer-Verlag, Berlin Heidelberg, pp. 227-247.

3. Guo, X. E. (2001) Biomechanics and Remodeling of Trabecular Bone, in Recent Advances in Biomechanics, Edited by C. Zhu and M. Long, Chinese Higher Education Press and Springer-Verlag, pp. 120-129.

4. Tang, Z., Chao, G., Tucay, A., Takai, E., Djukic, D., Lind, M. L., Hung, C. T., Guo. X. E., West, A., Osgood, R., and Yardley, J. T. (2003) XYZ on a Chip: Nanoscale Fabrication, Fluidics, and Optics Directed Toward Applications Within Biology and Medicine, in Organic Nanophotonics, Edited by F. Charra, V.M. Agranovich, and F. Kajzar, Kluwer Academic Publishers, Dordrecht, Netherlands, pp127-138.

5. Guo, X. E., Lu, H. H., Likhitpanichkul, M., and Mow, Van C. (2004) The Role of Biomechanics in Functional Tissue Engineering for Articular Cartilage, in Frontiers in Biomedical Engineering, Edited by N. H. C. Hwang and S. L.-Y. Woo, Kluwer Academic/Plenum Publishers, Chapter 3, 37-60.

6. Guo, X. E. (2007) Mechanotransduction in Bone Cell Network in Biomechanics at Micro- and Nanoscale Levels, Volume III, Edited by Hiroshi Wada, World Scientific Publishing.

7. Guo, X. E., Liu, X. S., and Wehrli, F. W. (2009) Advanced Structural Assessment of Bone Using CT and MRI in Osteoporosis in Men: The Effects of Gender on Skeletal Health, 2nd Edition, Edited by Eric Orwoll, John P. Bilezikian, and Dirk Vanderschueren, Elsevier.

Papers in Special Proceedings or Issues

1. Mow, V. C., Guo, X. E., Sun, D. N. and Lai, W. M. (2000) Changes in the Mechano-electrochemical Potential in the Extracellular Matrix Surrounding Chondrocytes, ASME Symposium on Mechanics in Biology, AMD-242/BED-46, pp. 215-228.

2. Lai, W. M., Sun, D. N., Ateshian, G. A., Guo, X. E. and Mow, V. C. (2000) Effects of Inhomogeneous Fixed Charge Density on the Electrical Signals for Chondrocytes in Cartilage, ASMS Symposium on Mechanics of Biology, AMD-242/BED-46, pp. 201-213.

3. Spalazzi, J. P., Dagher, E., Doty, S. B., Guo, X. E., Rodeo, S. A., and Lu, H. H. (2006) In vivo Evaluation of A Tri-phasic Composite Scaffold for Anterior Cruciate Ligament-to-Bone Integration, Conf Proc IEEE Eng Med Biol Soc. 1:525-528.

4. Guo, X. E. (2008) What is nanomechanics of bone and why is it important? J Musculoskelet Neuronal Interact, 8(4): 327-328.

5. Guo, X. E. (2008) Nanomechanics and bone tissue quality, J Musculoskelet Neuronal Interact, 8(4): 325-326.

6. Xu, F., Lu, T., and Guo, X. E. (2010) Multi-scale biothermal and biomechanical behaviours of biological materials, Philos Transact A Math Phys Eng Sci, 13; 368(1912): 517-519.

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